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Cytokine Molecular Biology
A Practical Approach
New Edition
Edited by Fran Balkwill
224 pages
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line figures
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246x189mm
978-0-19-963857-4
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Paperback
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09 November 2000
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This item is printed to order. Items which are printed to order are normally despatched and charged within 5-10 days.
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Cytokine Molecular Biology concentrates on molecular biology techniques for the study of cytokines, cytokine receptors, and cytokine driven processes. Updated topics from the previous edition are: the cloning and expressing cytokine genes;; the detection of cytokine mRNA; receptor binding studies; the PC-specific phosphslipase C and sphingomylinases. In addition, new topics covered are the purification, sequencing, and synthesis of cytokines; studying cytokine gene polymorphisms; the use of proteomics in cytokine research; and the Jak/STAT and MAPK signalling pathways. Written by experts in the field, Cytokine Molecular Biology and Cytokine Cellular Biology form a comprehensive and essential guide to cytokine
research. Readership: Biomedical scientists and technicians, especially those interested in cytokines.
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Edited by Fran Balkwill, Biological Therapeutics Laboratory, ICRF Contributors:
W. Declercq, M. Logghe, W. Fiers and R. Contreras, Laboratory of Molecular Biology, Flanders Interuniversity, Institute for Biotechnology, University Ghent; Francesco S. DiGivonne, Nicola J. Camp, Angela Cox, Adeel G. Chaudhary, Julian A. Sorrell, Alison Crane and Gordon W. Duff, University of Sheffield, Division of Molecular Medicine; Chris Scotton and Frances Burke, Biological Therapy Laboratory, Imperial Cancer Research Fund; Sofie Struyf, Anja Wuyts and Jo Van Damme, Rega Institute for Medical Research, Laboratory of Molecular Immunology, University of Leuven,
Belgium; Lara Izotova and Sidney Pestka, Department of Molecular Genetics and Microbiology, UMDNJ-Robert Wood Johnson Medical School, USA; B. M. J. Foxwell, A.E. Hunt, F.V. Lali and C. Smith, Kennedy Institute of Rheumatology, Cytokine and Immunology Division, London; Stephen Schütze and Martin Krönke, Institute of Immunology, University of Kiel, Germany; Thomas M. Leber and Adelina Rogowska, Centre for Proteoma Analysis in Life Sciences, Denmark; George Kassiotis, Manolis Pasparakis and George Kollias, Laboratory of Molecular Genetics, Hellenc Pasteur Institute
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Cloning and expression of cytokine genes
Methods for studying cytokine gene polymorphisms
Northern analysis, RT-PCR, Rnase protection, cDNA array systems and in situ hybridization detection of cytokine messenger RNA
Purification, sequencing and synthesis of cytokines and chemokines
Receptor binding studies
Cytokine signalling
Cytokine receptor signalling pathways: PC-specific phospholipase C and sphingomyelinases
Proteome analysis in cytokine research
Conditional and fixed cytokine gene modification in transgenic and mutant mice
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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