This is the only in-depth, single author survey of heart development. It will provide a more systematic, up-to-date synthesis of the subject than any other volume, spanning the range from classical anatomical studies to recent findings in molecular biology. It also covers topics that are often omitted from discussions of heart development, such as myocardial function, cardiac innervation, and conduction development and clinical correlates will be discussed throughout. The book is beautifully illustrated by Karen Waldo, an artist who has collaborated with Dr. Kirby for many years.
Readership: Biomedical postgraduate students, medical students, cardiologists, paediatric cardiologists, any health care professional involved with children who have heart defects, the biomedical research community, evolutionary developmental biology community.
Margaret Loewy Kirby, Professor of Pediatrics, Cell Biology, and Biology, Duke University Medical Center, USA
"This book takes on the daunting task of making something most consider labyrinthine, clearly understandable." - Doody's Notes
"This is a book that I looked forward to receiving and I have not been disappointed. It is the only contemporary, in-depth, single author reference on heart development - a complex subject which takes a book to begin to do justice to the detail and breadth of current knowledge. ...I recommend this book both to those who have and those who have yet to develop fascination for the subject." - British Journal of Hospital Medicine, Vol 68, No 11
1: An Overview of Cardiac Morphogenesis 2: Vascular Development 3: Cardiogenic Fields and Heart Tube Formation 4: Induction and Differentiation of the Working Myocardium 5: Tony Creazzo: Functional Developmental Biology of the Myocardium 6: Development of the Poles of the Heart 7: Molecular Control of Looping 8: Chamber Specification and Ventricular Septation 9: Endocardium, Cardiac Cushions, and Valve Development 10: Epicardium and Coronary Vessel Development 11: Neural Crest, Great Arteries and Outflow Septation 12: Development of the Cardiac Pacemaking and Conduction System 13: Innervation of the Developing Heart 14: Co-authored with Fred Schachat: Evolutionary Developmental Biology of the Heart 15: Some New Insights into the Embryogenesis of Heart Malformations in the Context of Syndromes 16: Myocardial Stem Cells Appendix I Glossary
