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The Spectrum of Renal Osteodystrophy
Edited by Tilman Drueke and Isidro Salusky
596 pages
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numerous black and white photographs and tables
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240x168mm
978-0-19-263230-2
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Hardback
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20 December 2001
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This item is printed to order and supplied on a firm sale basis. Items which are printed to order are normally despatched and charged within 5-10 days.
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- Detailed description of the broad spectrum of renal bone disorders in adults and children
- Discusses implications for growth in children with end-stage renal disease
- Covers diagnosis, treatment and pathogenesis of secondary hyperparathyroidism
- Overviews diagnosis, treatment and pathogenesis of adynamic bone disease
- Reviews soft tissue calcifications and cardiovascular disease
- Deatails the role of cytokines and growth factors in renal bone disease
- Discusses role of parathyroid hormone related peptide and receptor in skeletal development
It has been known for more than a century that patients with renal failure develop bone deformities and osteoarticular complications leading to pain and frequently disabling consequences for physical activity; in addition, growth retardation is a frequent complication in children with advanced renal insufficiency. In recent years there have been major advances in the understanding and treatment of the complications described under the term "renal osteodystrophy". In recent years, our understanding of the underlying causes and mechanisms involved in these complications has made major progress. In addition, new drugs have
been developed that will have a major impact in the prevention and treatment of renal osteodystrophy. The purpose of this book is to provide a state of the art overview of the various forms of renal osteodystrophy. Our aim is further to bring to the attention of adult and pediatric nephrologists, other specalists and practitioners the new developments in this area and to discuss their potential role in the treatment and prevention of the abnormalities of bone and mineral metabolism that occur in children and adults with renal failure.Readership: Adult and pediatric Nephrologists, renal transplant physicians, Endocrinologists and rheumatologists
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Edited by Tilman Drueke, Division of Nephrology, Necker Hospital,Paris, and Isidro Salusky, Director of Pediatric Dialysis Program, UCLA School of Medicine, California
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Part I: General aspects of bone turnover and growth
1: New aspects of bone biology (de Vernejoul, Marie)
Part II: Normal parathyroid function and PTH action
2: Regulation of PTH secretion and synthesis and of parathyroid cell proliferation (Silver, Kilav, Sela-Brown, Naveh-Many)
3: Roles of parathyroid hormone-related peptide and the PTH/PTHrP receptor in skeletal development: implications for growth in children with end-stage renal disease (Jüppner, Segre)
Part III: Pathogenesis of secondary uremic hyperparathyroidism
4: Abnormal PTH synthesis, secretion and metabolism; peripheral tissue resistance to PTH; pathologic parathyroid parathyroid cell growth and apoptosis (Drüeke, Rodriguez)
5: Parathyroid gland function in patients with renal failure (Goodman)
Part IV; Vitamin D metabolism and action in chronic renal failure
6: Vitamin D metabolism and action in chronic renal failure (Hsu, Young)
Part V: Pathogenetic and clinical aspects of renal bone disease
7: Cytokines and growth factors in renal bone disease (Martin, González)
8: Osteitis fibrosa, osteomalacia and mixed bone lesions (Ramirez, Felsenfeld)
9: Adynamic bone disease in uraemia (Fournier, Morinière, Said, Oprisiu, Tataru, Brazier, Marié, Cohen Solal)
10: Osteoporosis in uraemia (Fournier, Mazouz, Granos, Fardellone, Marié, Brazier, Cohen Solal)
11: Dialysis-associated amyloidosis (Bardin)
12: Bone diseases in children with chronic renal failure (Salusky, Kuizon)
Part VI: Soft tissue calcification in chronic renal failure
13: Soft tissue calcification in chronic renal failure (Rostand, Thornley-Brown)
Part VII: Non-invasive and invasive diagnosis of renal bone disease
14: Classical serum biochemistry and new biochemical markers (Schmidt-Gayk, Roth, Bregulla, Reichel, Halleen, Ritz, Drüeke)
15: X-ray, US, CT and MR imaging of skeleton and joints (Laredo, Bardin)
16: Imaging and intervention of parathyroid hyperplasia (Fukagawa, Kitaoka, Tominaga, Kuokawa)
17: The use of bone histomorphometry in renal osteodystrophy (Goodman)
Part VIII: Prophylaxis and treatment of renal osteodystrophy
18: Medical therapy in predialysis chronic renal failure (Coen)
19: Medical therapy in dialysis patients (Ritz, Schömig, Odoni)
20: Management in renal transplant recipients (Cunningham)
21: New vitamin D analogues and calcimimetics (Coburn, Maung, Frazaõ, Elangovan)
22: Surgical management (Sarfati, Drüeke)
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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