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Risk Assessment and Management in Cancer Genetics
Edited by Fiona Lalloo, Bronwyn Kerr, J. M Friedman, and D Gareth R. Evans
288 pages
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numerous line drawings, tables and halftones. 4 pp colour plates
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240x168mm
978-0-19-852960-6
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Paperback
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29 September 2005
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- Includes straightforward methods for the estimation of cancer risk to enable the reader to provide this information quickly when working in the clinic
- A practical guide to genetic testing to help the reader decide how to undertake testing
- Provides a comprehensive guide to the management of familial cancers to help the reader determine how to manage patients with a family history
The need to expand expertise in cancer genetics beyond highly specialized genetics clinics is increasingly being recognized. In response, this practical book provides oncologists, specialist nurses, genetic counsellors, family doctors, and geneticists with comprehensive and easy-to-use guidelines on risk assessment and appropriate management.
The book focuses on common familial cancers such as breast, colorectal, ovary, prostate and melanoma, and separate chapters cover cancer predisposing syndromes such as neurofibromatosis, familial adenomatous
polyposis and their management.Readership: Genetics trainees, genetic counsellors, oncologists, specialist nurses, and family doctors.
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Edited by Fiona Lalloo, Consultant Clinical Geneticist, Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital, Manchester, UK, Bronwyn Kerr, Consultant Clinical Geneticist, Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital, Manchester, UK, J. M Friedman, Professor of Medical Genetics, University of British Columbia, Vancouver, Canada, and D Gareth R. Evans, Professor in Medical Genetics, Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital, Manchester, UK Contributors:
Jillian M Birch, Professor,
CRC Paediatric and Familial Research Group, Royal Manchester Childrens Hospital, Manchester, UK
John Burn, Professor of Clinical Genetics, Institute of Human Genetics, International Centre for Life, Newcastle upon Tyne, UK
Susan Domchek, Associate Professor of Medicine, University of Pennsylvania, Philadelphia, USA
Fiona Douglas, Consultant in Clinical Genetics, International Centre for Life, Newcastle upon Tyne, UK
Rosalind Eeles, Senior Lecturer in Cancer Genetics & Clinical Oncology, Institute of Cancer Research; Honorary Consultant, Royal Marsden Hospital NHS Trust, UK
D Gareth Evans, Professor of Clinical Genetics, Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital, Manchester, UK
Jan M
Friedman, Professor, Department of Medical Genetics, University of British Columbia, Vancouver, Canada
Richard S Houlston, Senior Lecturer, Section of Cancer Genetics, Institute of Cancer Research, Sutton, UK
Sameer Jhavar, Clinical Research Fellow in Cancer Genetics, Institute of Cancer Research, Royal Marsden Hospital NHS Trust, UK
Bronwyn Kerr, Consultant Clinical Geneticist, Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital, Manchester, UK
Fiona Lalloo, Consultant Clinical Geneticist, Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital, Manchester, UK
Eamonn Maher, Professor of Medical Genetics, Department of Paediatrics and Child Health, University of Birmingham,
UK
Barbara C McGillivray, Professor of Medical Genetics, Children's & Women's Health Centre of British Columbia,
Vancouver, Canada
Fred Menko, Consultant Clinical Geneticist, Department of Clinical Genetics and Human Genetics, VU University Medical Center, Amsterdam, The Netherlands
Pål Moller, Consultant in Clinical Genetics, Unit of Medical Genetics, The Norwegian Radium Hospital, Oslo, Norway
Patrick Morrison, Professor of Medical Genetics, Belfast City Hospital, Belfast, Northern Ireland
Eamonn Sheridan, Consultant in Clinical Genetics, St James Hospital, Leeds, UK
Hans Vasen, Internist, The Netherlands Foundation Detection Hereditary Tumours, Leiden, The Netherlands
Barbara L Weber, University of
Pennsylvania, Philadelphia, USA
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"One of the commonest questions to a Clinical Genetics department is 'what do I do for this patient with a family history of cancer?' While most departments have guidelines for referral, these are intended to be for quick, easy-view reference. For those many clinicians who would like a little more detail, Lalloo and colleagues have produced this practical text with a worldwide list of contributors...it is easy to find the information you need in this book. Read it from cover to cover if it is valuable to your training or practice (or if you just like the subject) and you will have a comprehensive knowledge of what cancer genetics is about; keep it for reference, dipping into the particular bit you need from time to time, and your clinical genetics
colleagues will be very impressed with your knowledge." - Ulster Medical Journal
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Introduction
1: Bronwyn Kerr: How to evaluate a family history
2: Fred Menko: Guidelines for referral in Europe
3: Susan Domchek & Barbara L Weber: Guidelines for genetic counselling, testing and referral in North America
4: D Gareth Evans, Pål Moller & Bronwyn Kerr: Principles and applications of gene testing for common cancers
Risk assessment of common malignancies
5: D Gareth Evans, Bronwyn Kerr & Fiona Lalloo: Risk estimation in breast cancer
6: Fiona Lalloo: Risk estimation in colorectal cancer
7: D Gareth Evans: Risk estimation in ovarian cancer
8a: Pål Moller: Management of familial breast and ovarian cancer in Europe
8b: Barbara C McGillivray: Management of familial breast and ovarian cancer in North America
9: E Sheridan and R S Houlston: Management of familial adenomatous polyposis and other inherited polyposis syndromes
10: H F A Vasen, J Burn, E Sheridan, R S Houlston & F Douglas: Management of hereditary non-polyposis colorectal cancer
11: Sameer Jhavar & Rosalind Eeles: Management and risk assessment of less common familial cancers
Inherited cancer syndromes
12: J M Friedman: The neurofibromatoses
13: Eamonn R Maher: von Hippel-Lindau disease
14: Fiona Lalloo: Multiple endocrine neoplasias
15: D Gareth Evans: Gorlin Syndrome
16: J M Birch: The Li-Frameni Syndrome
17: Fiona Lalloo & D Gareth Evans: Other tumour predisposing syndromes
18: Patrick J Morrison: The ethical and insurance issues of cancer genetics
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Heather McLannahan
£19.99
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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