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Psychiatric Genetics and Genomics
Edited by Peter McGuffin, Michael J Owen, and Irving I Gottesman
504 pages
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240x168mm
978-0-19-856486-7
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Paperback
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23 September 2004
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This item is printed to order and supplied on a firm sale basis. Items which are printed to order are normally despatched and charged within 5-10 days.
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- Genetics is one of the rapidly expanding areas of psychiatric research
- Understanding the molecular neurobiology of psychiatric disorders will lead to the development of more specific drugs
- Genetic testing will help in predicting responses to treatment and in counselling patients and relatives
Revised for paperback edition, with new appendices
Genetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may have psychiatric presentations.
The first section of the book introduces the reader to molecular biology and the techniques of molecular genetics. The coverage then moves on to consider the genetics of normal and abnormal development,
followed by a look at the genetics of abnormal behaviour in adults. This section includes, amongst others, consideration of personality disorders, schizophrenia and the dementias. The final section considers the applications of the work and covers issues such as counselling and ethics, closing with a look to the future.
The editors are internationally renowned figures in this field and they have invited a team of equally eminent chapter authors.
Readership: Psychiatrists, clinical psychologists, geneticists, neuroscientists and neurologists
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Edited by Peter McGuffin, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Denmark Hill, London, UK, Michael J Owen, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK, and Irving I Gottesman, University of Minnesota, USA Contributors:
Maria Arranz, Institute of Psychiatry, Denmark Hill, London, UK
David Ball, Institute of Psychiatry, Denmark Hill, London, UK
Alastair Cardno, SGDP, Institute of Psychiatry, Denmark Hill, London, UK
Avshalom Caspi, Institute of Psychiatry, Denmark Hill, London, UK
Jill Clayton-Smith, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
David Collier, Institute of Psychiatry, Denmark Hill, London, UK
Nick Craddock, Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK
Thalia Eley, SGDP, Institute of Psychiatry, Denmark Hill, London, UK
Anne Farmer, SGDP, Institute of Psychiatry, Denmark Hill, London, UK
Irving Gottesman, Department of Psychology, University of Minnesota, Minneapolis, USA
Francesca Happe, Institute of Psychiatry, Denmark Hill, London, UK
Ian Jones, Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK
Lindsey Kent, Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK
Rob Kerwin, Institute of Psychiatry, Denmark Hill, London, UK
Malcolm Liddell, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
Peter McGuffin, SGDP, Institute of Psychiatry, Denmark Hill, London, UK
Terrie Moffitt, SGDP, Institute of Psychiatry, Denmark Hill, London, UK
Michael O'Donovan, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
Michael Owen, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
Robert Plomin, SGDP, Institute of Psychiatry, Denmark Hill,
London, UK
Jane Scourfield, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
Pak Sham, SGDP, Institute of Psychiatry, Denmark Hill, London, UK
Anita Thapar, Department of Child and Adolescent Psychiatry, Royal Manchester Children's Hospital, Manchester, UK
Julie Williams, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
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"The advent of the genomic era and recent progress in the fields of statistics and computation methodology are neatly balanced with the traditional cornerstones of psychiatric genetics, such as twin and adoption studies, in this impressive text on psychiatric genetics and genomics." - American Journal of Psychiatry Vol 162, No 11 "From reviews of the hardback:" "It is timely to see such an excellent textbook... Aimed at graduate level students, this book is complex enough to be thorough, but clear with enough background to be accessible... the coverage is comprehensive and the flow logical... The text is uniformly well written and achieves a successful integration." - The Lancet "A good
introduction and reference book for professionals interested in psychiatric genetics such as psychiatrists, clinical psychologists and neuroscientists... the book you want to have on your bookshelf to look up material and obtain a complete and balanced picture of the field." - Psychological Medicine
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Part 1: Basic Principles
1: Owen & O'Donovan: Basic molecular genetics
2: McGuffin & Cardno: Quantitative genetics
3: Sham & McGuffin: Linkage and association
Part 2: The Genetics of Normal and Abnormal Development
4: Plomin, Happe & Caspi: Personality and cognitive abilities
5: Thapar & Clayton-Smith: Genetics of mental retardation
6: Williams: Reading and language disorders
7: Thapar: Childhood disorders
Part 3: The Genetics of Abnormal Behaviour in Adult Life
8: McGuffin, Moffitt & Thapar: Personality disorders
9: Jones, Kent & Craddock: Genetics of affective disorders
10: Owen, O'Donovan & Gottesman: Schizophrenia
11: Ball & Collier: Substance misuse
12: Eley, Collier & McGuffin: Anxiety and eating disorders
13: Liddell, Williams & Owen: The dementias
D - Applications and Implications
14: Kerwin & Arranz: Pharmacogenetics
15: Scourfield & Owen: Genetic counselling
16: Farmer: Ethical considerations
17: Owen, McGuffin & Gottesman: The future and post-genomic psychiatry
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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