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Jim Cassidy, Donald Bissett...
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Highly commended in the oncology category of the British Medical Association Book Awards 2010
Opioids in Cancer Pain
Second Edition
Edited by Mellar P. Davis, Paul A. Glare, Janet Hardy, and Columba Quigley
504 pages
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33 black-and-white line drawings
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246x171mm
978-0-19-923664-0
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Hardback
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28 May 2009
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- Editors from 3 continents have produced a truly global perspective on the use of opioids in malignant disease
- Aids understanding of opioids and their effectiveness, essential to any clinician prescribing this type of drug
- Includes a review of all the major opioids
New to this edition - An editor from the UK, Columba Quigley, has joined the established editor team of Mellar Davis, Paul Glare and Janet Hardy, making the new edition even more international in scope
- New chapters on opioids in paediatrics, and opioids in developing countries, address the unique needs of these patient groups
- More focused attention on the differing uses of opioids, as separate chapters are devoted to dosing strategies in acute pain, and dosing strategies in chronic pain
- Buprenorphine has been added to the list of opioids covered, reflecting its common use in Europe and the debate surrounding its use in the US
- Organ failure is now covered
- Issues of addiction and substance abuse are now addressed
- The palliative care perspective has been strengthened, with the role of opioids in the terminal phase now included
- Incorporates new studies in opioid pharmacogenetics, a topic which may have significant implications for the use of these drugs in the future
Opioids have become invaluable in modern medicine but it is essential that they are prescribed with an understanding of the complex pharmacology behind their effectiveness; without this, they will frequently fail to achieve their enormous potential of pain relief, minimal side effects, and improved function. In addition, opioids come with problems, including side effects such as constipation, respiratory depression, and sedation, as well as the potential for substance abuse. Clinicians handling the complex pain problems of cancer patients must incorporate the insight of basic
scientists and pharmacologists, and this new edition of this comprehensive text brings together a wealth of experience from those involved in all aspects of opioids, with a view to improving both clinician understanding and patient care.
The text includes comprehensive coverage of the principles of opioid pharmacodynamics, pharmacokinetics, and pharmacogenetics. A chapter is dedicated to each of the main opioids, with topics such as structure, routes of administration, toxicity, drug interactions, and effects on organ function included within each one. The book concludes with several chapters dedicated to discussion of the major issues relevant to opioid use, including substance abuse, dosing strategies for acute and chronic pain, patient controlled analgesia,
equianalgesia, spinal opioids, pain that doesn't respond to opioids, and the terminal phase.
This text is the most complete and extensive work available on the use of opioids for cancer pain, and is an important reference for those clinicians treating individuals with cancer.Readership: This book is compulsory reading for anyone involved in administering opioids for the treatment of cancer pain; this includes palliative care doctors, oncologists, pain specialists and pharmacists.
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Edited by Mellar P. Davis, Director of Research, Harry R. Horvitz Center of Palliative Medicine, Taussig Cancer Center, Division of Solid Tumor, Cleveland Clinic, USA, Paul A. Glare, Chief, Pain and Palliative Care Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA, Janet Hardy, Director of Palliative Care, Mater Health Services, South Brisbane, Queensland, Australia, and Columba Quigley, Formerly Consultant/Honorary Senior Lecturer in Palliative Medicine, Hammersmith Hospitals Trust, London, UK Contributors:
Costantino Benedetti, Clinical Professor,
Department of Anesthesiology, The Ohio State University Medical Center, USA
Mellar P. Davis, Director of Research, The Harry R. Horvitz Center for Palliative Medicine, Cleveland Clinic Foundation, Ohio, USA
Ross Drake, Clinical Director Paediatric Complex Pain and Palliative Care Services, Starship Children's Hospital, Auckland, New Zealand
Paul A. Glare, Head, Palliative Care, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; Clinical Associate Professor, Department of Medicine (Central Clinical School), University of Sydney
Tony Hall, Assistant Director of Pharmacy (Clinical), Mater Health Services, South Brisbane, Australia
Janet Hardy, Director of Palliative Care, Mater Health Services, South Brisbane, Queensland,
Australia
Kenneth C. Jackson, Pacific University, School of Pharmacy, Hillsboro, Oregon, USA
Kenneth L. Kirsh, Pharmacy Practice and Science, University of Kentucky, USA
Mhoira Leng, Medical Director, Cairdeas International Palliative Care Trust, Scotland
Gavril W. Pasternak, Member and Attending Neurologist, Head, Laboratory of Molecular Neuropharmacology, Memorial Sloan-Kettering Cancer Center, New York, USA
Steven D. Passik Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, New York, USA
Steven Paquelet, Assistant Clinical Professor, Department of Anesthesiology, The Ohio State University Medical Center, USA
Columba Quigley, Consultant and Honorary Senior Lecturer in
Palliative Care, Hammersmith Hospital, London, UK
Lauren J. Rogak, Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, New York, USA
Joy Ross, St Joseph's Hospice, London, UK
Tatiana D. Starr, Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, New York, USA
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"Each chapter is well referenced, providing an excellent critical review of the literature in this field." - American Journal of Epidemiology "This is the best current textbook on the clinical use of opioids in cancer pain (and in chronic benign pain)." - BMA Medical Book Competition 2010 "...well set out with the good use of headings... well-referenced... the editors are to be congratualted for putting together what remains the premier reference on opioids in cancer pain" - Roger Woodruff
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1: Mellar P. Davis and Gavril W. Pasternak: Opioid receptors and opioid pharmacodynamics
2: Kenneth C. Jackson, Mellar P. Davis & Columba Quigley: Opioid pharmacokinetics
3: Mellar P. Davis: Liver disease and exogenous opioid pharmacokinetics
4: Janet Hardy & Columba Quigley: Opioids in renal failure
5: Janet Hardy & Kenneth C. Jackson: Codeine
6: Mellar P. Davis: Hydrocodone
7: Mellar P. Davis & Paul A. Glare: Tramadol
8: Paul A. Glare: Dextropoxyphene
9: Paul A. Glare: Morphine
10: Paul A. Glare & Mellar P. Davis: Oxycodone
11: Tony Hall & Janet Hardy: The lipophilic opioids - fentanyl, alfentanil, sufentanil and remifentanil
12: Mellar P. Davis: Buprenorphine
13: Columba Quigley & Mellar P. Davis: Methadone
14: Columba Quigley & Paul A. Glare: Hydromorphone
15: Mellar P. Davis: Levorphanol
16: Janet Hardy & Columba Quigley: Diamorphine
17: Paul A. Glare: Oxymorphone
18: Paul A. Glare: Choice of opioids and the WHO ladder
19: Joy Ross & Columba Quigley: Pharmacogenetics and opioids
20: Janet Hardy, Columba Quigley & Joy Ross: Opioid rotation
21: Mellar P. Davis & Kenneth C. Jackson: Equianalgesia
22: Mellar P. Davis: Dosing strategies for acute pain
23: Mellar P. Davis: Opioid dosing strategies for chronic pain and the management of opioid side effects
24: Mellar P. Davis: Patient controlled analgesia
25: Costantino Benedetti, Steven Paquelet & Mellar P. Davis: Spinal opioids in cancer pain
26: Mellar P. Davis: Opioid poorly responsive pain, physical dependence, tolerance and opioid-induced hyperalgesia
27: Mhoira Leng: Opioids in special populations: developing countries
28: Ross Drake: Opioids in special populations: pediatric population
29: Janet Hardy: Opioids in the terminal phase
30: Kenneth L. Kirsh, Tatiana D. Starr, Lauren J. Rogak & Steven D. Passik: Cancer pain and substance abuse
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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