• A focus on generic components of extra- and intracellular signalling pathways allows the student to gain a thorough understanding of the underlying principles of cell signalling before exploring how the individual components interact to form complex signalling pathways
• The ubiquity of key signalling mechanisms is highlighted, enabling students to see how similar mechanisms are conserved and harnessed in many different biological systems
• Two colour artworks enliven the text, and enable students to visualise the processes and interactions described more easily
• The student is directed to carefully chosen further reading articles, allowing them to readily explore key topics in more detail
• Online Resource Centre includes figures from the book available to download to facilitate lecture preparation

New to this edition

• New two colour text design, to enhance the educational value of the custom-drawn illustrations
• Expanded introductory material, to give all students a firmer platform on which to build their knowledge of the subject
• Enhanced coverage of G proteins, cytokines, and kinases to reflect recent advances in our knowledge and understanding of these signalling components
• Detailed coverage of nitric oxide signalling, a theme which is now central to cell signalling, but which is often neglected in other texts
• Enriched pedagogy includes new Boxes, giving definitions of key terms and expanding on key concepts which are introduced in the text, and end of chapter summaries, both of which make the book even easier to learn from
• All artwork available to download from the book's companion web site

Readership: Advanced undergraduate and beginning graduate students of cell and molecular biology, and biochemistry. Also of interest to students of other biological disciplines who need to have an understanding of cell signalling (for example, immunology, and developmental biology).

John Hancock, Reader in Molecular Biology, Faculty of Applied Science, University of the West of England, Bristol, UK

1: Aspects of Cell Signalling
2: Extracellular Signals - Hormones, Cytokines, Growth Factors
3: Detection of Extracellular Signals: The Role of Receptors
4: Protein Phosphorylation, Kinases and Phosphatases
5: Cyclic Nucleotides, Cyclases and G Proteins
6: Inositol Phosphate Metabolism and Roles of Membrane Lipids
7: Intracellular Calcium: Its Control and Role as an Intracellular Signal
8: Reactive Oxygen Species, Reactive Nitrogen Species and Redox Signalling
9: Insulin and the Signal Transduction Cascades it Invokes
10: Perception of the Environment
11: Life, death, and Apoptosis
12: Cell Signalling: Importance, Complexity and Future