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Physical Chemistry for the Life Sciences
Peter Atkins and Julio de Paula
656 pages
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Numerous halftones and line drawings
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252x200mm
978-0-19-928095-7
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Hardback
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18 August 2005
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- The only text to offer a fully integrated approach to the study of physical chemistry and biology; lecturers and students alike have a text that is truly tailor-made for their course for the first time
- Presents a conceptually challenging interdisciplinary subject with the clarity and lucidity for which the authors are renowned, making it the text of choice for teaching and learning from
- Every section of the text presents a core physical chemistry concept in tandem with its biological significance; the student is in no doubt as to the relevance of the physical concept to the study of biology
- Written to be flexible enough to be used to teach from a biochemistry perspective or from a physical chemistry perspective, allowing the lecturer to tailor their use of the book to meet the goals of their course
- All applications and exercises relate directly to life sciences systems, further contextualising the physical chemistry content for life sciences students
- The presentation of maths, and calculus in particular, covers only the essentials and each mathematical step is carefully justified, in order to build the students' confidence in the mathematical concepts underlying the subject
- Online Resource Centre:
full colour artwork from the text in downloadable form, to facilitate lecture preparation, and interactive Living Graphs and web links, to support students' self-learning
The behaviour of those macromolecules and molecular assemblies that have vital roles in all living organisms is grounded in physical chemistry. Physical principles determine the stability of proteins and nucleic acids, the rate at which biochemical reactions proceed, the transport of molecules across biological molecules; they allow us to describe structure and reactivity in complex biological systems, and make sense of how these systems operate.
Physical Chemistry for the Life Sciences fills a void in the textbook market by offering a balanced presentation of the
concepts of physical chemistry, and their extensive applications to biology and biochemistry. It is written to straddle the worlds of physical chemistry and the life sciences and to show students how the tools of physical chemistry can elucidate and illuminate biological questions.
Opening with a suite of chapters on Biochemical Thermodynamics, with a focus on energy conversion in biological cells and the factors that stabilize proteins, nucleic acids, and cell membranes, the book goes on to explore the Kinetics of Life Processes, examining the rates of chemical reactions, how rates can help characterise the mechanism of a reaction, and how enzymes affect reaction rates. A third section, Biomolecular Structure, looks at how concepts of physical chemistry can be used
to establish those 'rules' that govern the assembly of complex biological structures, while the final section, Biomolecular Spectroscopy, describes the major techniques in biochemistry that are being applied to help us to explore biochemical processes and systems ever further.
Physical Chemistry for the Life Sciences places emphasis on clear explanations of difficult concepts, with an eye toward building insight into biochemical phenomena. A rich palette of pedagogical features, including worked examples, illustrations, self-tests, and case studies, support student learning throughout, while special attention is given to providing extensive help to students with those mathematical concepts and techniques that are so central to a sound understanding of physical
chemistry.
Balancing clarity and rigor of exposition of basic concepts with extensive discussion of biological techniques and processes, Physical Chemistry for the Life Sciences is the perfect resource for every life science student who seeks to master those essentials of physical chemistry that underpin life itself.
Pedagogy:
- A Biochemical link at the start of each section explains how the physical chemistry content of the section is related to a biological concept, providing clear connections to students and acting as motivators for understanding
- Toolbox sections describe techniques, and link experimental method with physical chemistry concepts, so the student can understand how experimental techniques
are used to probe and solve chemical questions
- Maths comments explain mathematical relationships and background necessary for solving problems, providing guidance and insight to bolster student understanding
- Derivations present detailed derivations of key equations, and delineate intermediate steps, showing the student the enormous power of even simple mathematics
- Worked examples illustrate the concepts being presented, empowering the student to apply the concepts for themselves
- Self tests occur throughout the chapters, to enable students to immediately test their understanding
- Checklists of key ideas at the end of each chapter provide a bulleted list of the information students should grasp from the chapter, facilitating
student revision
- End of chapter exercises come in three varieties, to enable students to apply the concepts introduced and check their understanding:
- Discussion questions stimulate the qualitative understanding of problems
- Exercises assess quantitative understanding
- Projects stimulate more in-depth examination of questions at both a qualitative and quantitative level
Online Resource Centre
- Web links for each chapter, pointing students to interesting sources of related information and data, to facilitate self-directed learning
- A list of key equations for each chapter, to help students revise and master the key mathematical concepts that underpin the subject
- Living
graphs, which present graphs from the text in interactive format, and enable students to strengthen their learning
- Full colour artwork from the text in downloadable form, to facilitate lecture preparationReadership: First and second year undergraduates taking a first course in physical chemistry as part of a life science, biological chemistry, or biochemistry degree programme.
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Peter Atkins, Professor of Chemistry, University of Oxford, and Fellow of Lincoln College, Oxford, and Julio de Paula, Professor and Dean of the College of Arts and Sciences, Lewis and Clark College, Portland, Oregon, USA
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"this book provides an excellent insight into the subject of physical chemistry, understandable and suitable for both beginners and experts of chemistry." - Internal Journal of Biological Macromolecules, August 2006 "The authors succeed brilliantly in their aim to show that deep insights into the behaviour of biological systems can be gained by applying the principles of physical chemistry. I enjoyed reading this book and would recommend it without reservation to teachers and students alike." - Chemistry World, January 2006
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Prologue
Fundamentals
Part I
Biochemical Thermodynamics
1: The First Law
2: The Second Law
3: Phase Equilibria
4: Chemical Equilibrium
5: Thermodynamics of Ion and Electron Transport
Part II
Kinetics of Life Processes
6: The Rates of Reactions
7: Accounting for the Rate Laws
8: Complex Biochemical Processes
Part III
Biomolecular Structure
9: Dynamics of Microscopic Systems
10: The Chemical Bond
11: Molecular Interactions
12: Macromolecules and Self-Assembly
13: Statistical Aspects of Structure and Change
Part IV
Biomolecular Spectroscopy
14: Optical Techniques and Photobiology
15: Magnetic Resonance
Appendices
1: Units and Unit Conversions
2: Essential Concepts of Mathematics
3: Essential Concepts of Physics
4: Review of Chemical Principles
Data Section
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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