|
Also Recommended
|
|
|
William H. Elliott, Daphne C. Elliott
£32.99
|
|
|
|
|
Principles of Genome Function
Nancy Craig, Orna Cohen-Fix...
£43.99
|
|
|
|
|
|
Edward C. Holmes
£34.95
|
|
|
|
|
Molecular Biology of RNA
David Elliott and Michael Ladomery
460 pages
|
136 line drawings
|
265x195mm
978-0-19-928837-3
|
Paperback
|
02 December 2010
|
|
|
|
|
- The first student text to focus exclusively on the role of RNA in biological systems.
- Broad coverage encompasses all aspects of RNA biology, including transcription, splicing, and the role of RNAs in protein synthesis; RNAs as biological catalysts; and RNAs as regulatory molecules.
- Presents a review of our current understanding of the field, together with explanations of the experimental approaches used to gain this understanding.
- Extensive use of figures alongside careful explanations in the text help to introduce even the most challenging concepts as clearly as possible.
- An Online Resource Centre features additional teaching and learning resources for both students and lecturers.
For many years, RNA was thought to have something of a supplementary role in genome function - an intermediate in the flow of biological information from gene to protein. In recent years, however, the centrality of RNA as a key player in gene expression has become clear; it is far from being merely a staging post between gene and protein. Instead, new insights into RNA structure and function have revolutionized our view of molecular biology, and the role of RNA in the evolution of life itself.
Molecular Biology of RNA is the first student text to provide a broad survey of RNA
structure and function. It leads the reader through the life cycle of an RNA, placing particular emphasis on post-transcriptional events - including post-transcriptional processing and splicing - to reveal how hugely diverse gene products stem from a relatively modest gene pool. It also describes how RNA molecules have a range of biological functions beyond that of the messenger RNA, including roles as catalysts and regulatory molecules.
Throughout the book, descriptions of our current understanding of the field are augmented with examples of pioneer RNA researchers and their key experiments, demonstrating how we have reached our current level of understanding. Further, boxes illustrate the involvement of RNA in the aetiology of human disease, showing how an
understanding of the molecular biology of RNA is central to understanding disease processes and their potential treatment.
Molecular Biology of RNA is an essential course text for molecular biology students in the 21st century, capturing the excitement of a field that has changed our understanding of genome function forever.
Online Resource Centre
The Online Resource Centre to accompany Molecular Biology of RNA features:
For registered adopters:
Figures from the book in electronic format
Readership: Undergraduates and postgraduates studying any aspect of RNA biology as part of a broader
programme of study.
|
|
|
David Elliott, Professor of Genetics, Newcastle University, and Michael Ladomery, Reader in Biomedical Science and Principal Investigator, RNA Biology Group, School of Life Sciences, University of the West of England
|
|
|
"This comprehensive textbook is pitched at just the right level and explains the concepts in sufficient detail to make them come to life without swamping the uninitiated with confusing information and jargon. The authors have to be congratulated on the comprehensive nature of the textbook, which means that even RNA aficionados will find useful information within its pages." - Ilan Davis, University of Oxford in Development
"All aspects of RNA biology are described clearly... One type of molecule, one book, up to date... A book on RNA like this is just in time. I am planning to start a MSc course on just RNA and this would be the book to use.
" - Dr J Kooter, Vrije Universiteit Amsterdam
"There are currently no suitable textbooks (on Molecular Biology of RNA) that I am aware of, and thus this book fills a very useful niche.
" - Dr S Valadkhan, Case Western Reserve University
|
|
|
1: Introduction to Molecular Biology of RNA
2: RNA can form versatile structures
3: Catalytic RNAs
4: The RNA-binding proteins
5: Co-transcriptional pre-mRNA processing
6: Pre-mRNA splicing by the spliceosome
7: How pre-mRNAs are decoded by the splicing machinery
8: Regulated RNA processing - alternative splicing
9: Pre-mRNA splicing defects in development and disease
10: Nucleocytoplasmic traffic of messenger RNA
11: Nucleocytoplasmic traffic of non-coding RNA
12: Messenger RNA localization
13: Translation of messenger RNA
14: Stability and degradation of mRNA
15: RNA editing
16: The biogenesis of non-coding RNAs
17: The 'mega RNAs': long non-coding RNAs with important roles in epigenetic regulation of gene expression
18: The short non-coding RNAs and gene silencing
|
|
|
|
Recently Viewed
|
|
|
Volume One: Cheap Print in Britain and Ireland to 1660
Joad Raymond
£100.00
|
|
|
|
|
Peter Boxall, John Purcell...
£125.00
|
|
|
|
|
Peter Clarke
£95.00
|
|
|
|
|
The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
|
|
