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Introduction to Genomics
Arthur Lesk
440 pages
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80 colour line, 60 colour half tone illustrations
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246x189mm
978-0-19-929695-8
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Paperback
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22 February 2007
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- The author's widely-praised writing style leads the reader through a conceptually challenging subject in a clear, lucid way, building confidence in, and enthusiasm for, the subject from the outset
- Extensive learning tools throughout - and most notably the end of chapter exercises, problems and Weblems (web-based problems) - encourage and support self-directed learning, helping the student to master the subject through hands-on learning
- Special topics boxes and case studies augment the main text, enabling flexibility of use, and offering an extra level of detail for those studying the topic at a more advanced level
- Applications, discussed in context, draw ideas together and demonstrate the relevance of genomics in applied, practical settings, including agriculture, medicine, and forensics
- Presentation of required background information provides a 'primer' of the key molecular biological concepts on which genomics is founded - an ideal resource for those new to the subject, or those who need a quick refresher of essential concepts
- Online Resource Centre features an extensive range of resources for both lecturers and students, enhancing the value of the book as a teaching and learning tool
Our genome is the blueprint to our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. But it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed. But how do we identify the genes that make up our genome? How we determine their function? And how do different genes form the regulatory networks that direct the process of
life?
Introduction to Genomics is a fascinating insight into what can be revealed from the study of genomes: how organisms differ or match; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing.
Covering the latest techniques that enable us to study the genome in ever-increasing detail, the book explores what the genome tells us about life at the level of the molecule, the cell, the organism, the ecosystem and the biosphere. Learning features throughout make this book the ideal teaching and learning tool: extensive end of chapter exercises and problems help the student to grasp fully the concepts being presented, while end
of chapter WebLems (web-based problems) and lab assignments give the student the opportunity to engage with the subject in a hands-on manner.
The field of genomics is enabling us to analyze life in more detail than ever before; Introduction to Genomics is the perfect guide to this enthralling subject.
Online Resource Centre:
- Figures from the book available to download, to facilitate lecture preparation
- Answers to odd-numbered end of chapter exercises, and hints for solving end of chapter problems, to support self-directed learning
- Library of web links, for rapid access to a wider pool of additional resourcesReadership:
Intermediate and advanced biology, biomolecular science, and biochemistry undergraduates. Also of interest to postgraduate students requiring a primer on this subject.
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Arthur Lesk, Professor of Biochemistry and Molecular Biology, The Pennsylvania State University, USA.
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"This is an extraordinarily well-written book on genomics and related areas such as proteomics and systems biology. It is remarkable in its coverage of a very complex area. I was particularly impressed by the section on genomics which is well understood by the somewhat classical protein chemist." - Roger L. Lundblad in The Internet Journal of Genomics and Proteomics, July 2007
"Overall the author does an excellent job. Communicating the possibilities available in current biological research, uncovering the basis of life, to young scientists is essential if we are to realise the potential that genomics and systems biology promise. This book does very well, covering most of the bases in a straightforward and well-written manner. It is definitely good value and to be recommended for teaching introductory courses." - Dr Steve Russell in Bioessys, October 2007
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1: Introduction to Genomics
2: Comparative Genomics
3: Evolution and Genomic Change
4: Mapping, sequencing, annotation and databases
5: Microarrays
6: Proteomics
7: Systems Biology
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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