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Understanding depression
A translational approach
Edited by Carmine Pariante, Randolph M. Nesse, David Nutt, and Lewis Wolpert
400 pages
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43 line figures, 6 black & white photos and a 4 page colour plate section
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246x171mm
978-0-19-953307-7
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Paperback
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02 July 2009
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- Present an interdisciplinary review of depression, from basic science to clinical practice
- Shows how translational approaches to medicine can help us attain a deeper understanding of this complex illness
- Includes chapters from an international group of leading researchers and leading clinicians, making the content applicable throughout the world
Depression is a major cause of morbidity throughout the world. Given that between 8 and 12% of the population (in most countries) will suffer from depression at some point in their lives, it is clearly a significant public health problem. As our knowledge of this illness has expanded in recent years, it has become clear that depression can no longer be viewed as a simple disorder of the brain. It has to be seen as a series of behavioural and biological changes that span mind, brain, genes, and body - indeed affecting both psychological and physical health.
This book brings together world leaders in research on depression, to discuss, for the first time, in an interdisciplinary setting, both classical and innovative ideas to understand this devastating disorder. It presents neurobiological, psychological, genetic and evolutionary models, with a particular emphasis on the mechanisms linking the brain to the endocrine and the immune systems, and therefore linking depression to physical health.
Opening with a powerful, personal, account of depression, that conveys something of the all-consuming, debilitating, nature of this illness, the book then presents cutting edge research from those at the frontiers of work in this area. The book will be valuable for all those in the brain sciences seeking a state of the art
review of this global problem.Readership: Psychiatrists and clinical psychologists; neuroscientists
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Edited by Carmine Pariante, Institute of Psychiatry, Randolph M. Nesse, University of Michigan, David Nutt, University of Bristol, and Lewis Wolpert, University College London Contributors:
Katherine J Aitchison, SGDP, Institute of Psychiatry, King's College London, UK
Jose Amat, New York State Psychiatric Institute, New York, USA
Michael V Baratta,
Bettina Bewernick, Dept of Psychiatry, University of Bonn, Germany
Elisabeth B Binder, Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta GA, USA
Sondra T
Bland, Dept of Psychiatry, University of Texas, Austin, USA
Nathalie Castanon, Université Victor Ségalen Bordeaux 2, Bordeaux, France
Sabine Chourbaji, Zentralinstitut für Seelische Gesundheit, Mannheim, Germany
John C Christianson,
Stephan Claes, Universitair Psychiatrisch Centrum, Leuven University, Leuven, Belgium
Tony Cleare, Institute of Psychiatry, King's College London, UK
Becky Conway-Campbell, Henry Wellcome Lab for Integrative Neuroscience & Endocrinology, University of Bristol, UK
Philip J Cowen, Dept of Psychiatry, Warneford Hospital, Oxford, UK
Nick Craddock, Dept of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK
Bernard J Crespi, Simon Fraser
University, Dept of Biological Sciences, Burnaby, BC, Canada
B Czeh, Clinical Neurobiology Lab, German Primate Centre, Leibniz Institute for Primate Research, Göttingen, Germany
Robert Dantzer, Dept of Pathology, University of Illinois at Urbana-Champaign, Urbana IL, USA
A G Dayer, Dept of Neurosciences, University Medical Centre, University of Geneva, Switzerland
Timothy G Dinan, Dept of Psychiatry, Cork University Hospital, Cork, Ireland
I Nicol Ferrier, Institute of Neuroscience, The Medical School, Newcastle upon Tyne, UK
Peter Fitzgerald, Dept of Psychiatry, Cork University Hospital, Cork, Ireland
Sarah E Gartside, Institute of Neuroscience, The Medical School, Newcastle upon Tyne, UK
Peter Gass,
Zentralinstitut für Seelische Gesundheit, Mannheim, Germany
Nicole Geschwind, Dept of Psychiatry & Neuropsychology, Maastricht University, Maastricht, The Netherlands
Bhanu Gupta, SGDP, Institute of Psychiatry, King's College London, UK
C J Harmer,
Max Henderson, Dept of Psychological Medicine, Institute of Psychiatry, London, UK
Megan C Holmes, Endocrinology Unit, Centre for Cardiovascular Science, Queen's Medical Research Inst, Edinburgh, UK
Matthew Hotopf, Dept of Psychological Medicine, Institute of Psychiatry, London, UK
Matthew T Keener, Western Psychiatric Institute & Clinics, School of Medicine, University of Pittsburgh, Pittsburgh, USA
Robert Keers,
Keith W Kelley, Dept of
Pathology, University of Illinois at Urbana-Champaign, Urbana IL, USA
Monica Kelly Cowles, Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
Jacques Lestage, Université Victor Ségalen Bordeaux 2, Bordeaux, France
Stafford Lightman, Henry Wellcome Lab for Integrative Neuroscience & Endocrinology, University of Bristol, UK
Christoher A Lowry,
Paul Lucassen, Centre for Neuroscience, Swammerdam Inst of Life Sciences, University of Amsterdam, The Netherlands
Steven F Maier, Dept of Psychology, University of Colorado at Boulder, Boulder, CO, USA
Hamish McAllister-Williams, School of Neurology, Neurobiology & Psychiatry, Newcastle University, Newcastle upon Tyne
Peter
McGuffin, SGDP, Institute of Psychiatry, King's College London, UK
Peter Meerlo, Dept of Molecular Neurobiology, Centre for Behaviour & Neurosciences, University of Groningen, The Netherlands
Andrew H Miller, Dept of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
A S Naylor, Dept of Physiology, Faculty of Medicine & Health Sciences, University of Auckland, New Zealand
Charles B Nemeroff, Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
Randolph M Nesse, Dept of Psychology, University of Michigan, Ann Arbor, MI, USA
David Nutt, Psychopharmacology Unit, University of Bristol, UK
Jason C O'Connor, Dept of Pathology, University of Illinois
at Urbana-Champaign, Urbana IL, USA
C A Oomen, Centre for Neuroscience, Swammerdam Inst of Life Sciences, University of Amsterdam, The Netherlands
Michael J Owen, Dept of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK
Thaddeus W W Pace, Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
Carmine Pariante, Dept of Psychological Medicine, Centre for the Cellular Basis of Behaviour, Institute of Psychiatry, London, UK
Frenk Peeters, Dept. Psychiatry & Neuropsychology, EURON, Maastricht University, Maastricht, The Netherlands
Mary L Phillips, Dept of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Charles I Raison,
Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
K S Reid,
Robert R Rozeske,
Thomas E Schlaepfer, Dept of Psychiatry, University of Bonn, Germany
Jonathan R Seckl, Endocrinology Unit, Centre for Cardiovascular Science, Queen's Medical Research Inst, Edinburgh, UK
Daniel J Smith, Dept of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK
Andrew Steptoe, Dept of Epidemiology & Public Health, University College London, London, UK
Brittany Thompson,
Rudolf Uher, SGDP, Institute of Psychiatry, King's College London, UK
A M van Dam, Free University Medical Centre, Dept of Anatomy & Neurosciences, Amsterdam, The Netherlands
Jim van Os, Dept. Psychiatry & Neuropsychology, Maastricht University, Maastricht, The Netherlands
Linda R Watkins, Dept of Psychology, University of Colorado at Boulder, Boulder, CO, USA
Marieke Wichers, Dept. Psychiatry & Neuropsychology, EURON, Maastricht University, Maastricht, The Netherlands
C C Wiles,
Grzegorz Wisniewski,
Lewis Wolpert, Dept of Anatomy & Developmental Biology, University College London, UK
Caitlin S Wyrwoll, Endocrinology Unit, Centre for Cardiovascular Science, Queen's Medical Research Inst, Edinburgh, UK
Allan H Young, Dept of Psychiatry, University of British Columbia, Vancouver BC, Canada
Elizabeth Young, University of Michigan, Molecular & Behavioral Neuroscience
Institute, Ann Arbor, MI, USA
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1: Lewis Wolpert: Experiencing depression
2: Monica Kelly Cowles, Carmine Pariante & Charles B Nemeroff: Depression in the medically ill
3: Randolph M Nesse: Explaining depression: neuroscience is not enough, evolution is essential
4: Bernard J Crespi: Evolutionary genetics of affective disorders
5: Stephan Claes, Elisabeth B Binder & Charles B Nemeroff: Genetic factors in stress and major depression
6: Daniel J Smith, Michael J Owen & Nick Craddock: Bipolar disorder and unipolar depression: what is the genetic relationship?
7: Becky Conway-Campbell, C C Wiles & Stafford Lightman: The significance of dysregulated basal glucocorticoid pulsatility in affective disorders
8: Caitlin S Wyrwoll, Megan C Holmes & Jonathan R Seckl: Early life programming of affective function
9: Sabine Chourbaji & Peter Gass: Modeling depression by GR mutant animals?
10: Robert Dantzer, Jason C O'Connor, Nathalie Castanon, Jacques Lestage & Keith W Kelley: Cytokines and depression: experimental evidence and intermediate mechanisms
11: Paul Lucassen, Peter Meerlo, A S Naylor, A M van Dam, A G Dayer, B Czeh & C A Oomen: Do depression, stress, sleep disruption and inflammation alter hippocampal apoptosis and neurogenesis?
12: Steven F Maier, Jose Amat, Michael V Baratta, Sondra T Bland, John C Christianson, Brittany Thompson, Robert R Rozeske & Linda R Watkins: The role of the medial prefrontal cortex in mediating resistance and vulnerability to the impact of adverse events
13: Philip J Cowen & C J Harmer: Is it all monoamines?
14: Nicole Geschwind, Jim van Os, Frenk Peeters & Marieke Wichers: The role of affective processing in vulnerability to and resilience against depression
15: Elizabeth Young: PTSD and HPA axis: same hormones, different disorders
16: Timothy G Dinan & Peter Fitzgerald: Neuroendocrine and immune cross talk in major depression
17: Andrew H Miller, Thaddeus W W Pace & Charles I Raison: Neuropsychiatric effects of IFN-alpha: relevance to depression
18: Andrew Steptoe: Depression and coronary heart disease
19: Tony Cleare: Does depression induce pain and fatigue?
20: Matthew Hotopf & Max Henderson: Explaining the association between depression and mortality: a life course epidemiology approach
21: Allan H Young: Depression: unipolar or bipolar, what's the difference (and what does it matter anyway)?
22: Matthew T Keener & Mary L Phillips: Can neuroimaging help distinguish bipolar depression from major depressive disorder?
23: Bhanu Gupta, Robert Keers, Rudolf Uher, Peter McGuffin & Katherine J Aitchison: Pharmacogenetics of antidepressant response
24: R Hamish McAllister-Williams & Grzegorz Wisniewski: Can the EEG be used to predict antidepressant response?
25: Thomas E Schlaepfer & Bettina Bewernick: Can we use magnetic/electric fields to help in treatment resistant depression?
26: Sarah E Gartside, K S Reid & I Nicol Ferrier: Antiglucocorticoids in the treatment of affective disorders: from pre-clinical to clinical studies
27: David Nutt & Christoher A Lowry: How can we use current knowledge to improve antidepressant treatments?
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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