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RNA Viruses
A Practical Approach
Edited by Alan Cann
288 pages
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numerous figures, 13 halftones, 21 line drawings
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246x189mm
978-0-19-963716-4
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Paperback
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04 May 2000
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This item is printed to order and supplied on a firm sale basis. Items which are printed to order are normally despatched and charged within 5-10 days.
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- Provides an overview of fundamentals in RNA virus research.
- Covers many specialized techniques for studying viruses.
- Over 120 protocols and many figures.
- Essential volume for all laboratories involved in RNA virus research.
RNA Viruses: A Practical Approach is wide ranging in scope, from emerging technology such as reverse genetics and retrovirus vectors, to money saving tips - how to make your own silica particles for high efficiency RNA extraction and liposomes for cell transfection! Chapter one covers the fundamentals of investigating RNA virus genome structure at a molecular level. Chapters two and three describe techniques for mutagenesis of RNA genomes and analysis of transcription. Chapter four deals with RNA virus-encoded proteinases, an important aspect of the control of RNA virus gene expression. Chapter five considers retrovirus oncogenesis and chapter
six analysis of RNA virus quasispecies. Chapter seven describes systems for investigation of in vitro replication of positive-stranded viruses and chapter eight the packaging of RNA virus genomes. In addition to the technical aspects of reverse genetics and retrovirus vectors, both of the final two chapters also consider ethical aspects of these new technologies.Readership: Industrial virus research laboratories, public health laboratories and academia. Postgraduates reading biology and medicine.
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Edited by Alan Cann, Department of Microbiology and Immunology, University of Leicester Contributors: A. J. Easton, A.C. Marriott and C. R. Pringle, Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL; W.S. Barclay and J.W. Almond, Department of Microbiology, School of Animal and Microbial Sciences, University of Reading, PO Box 228, Reading, Berkshire RG6 2AJ; S. Makino, Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, Texas 77555-10109, USA; M.D. Ryan, M. Flint, M.OL.L. Donnelly, E. Byrne, and V. Cowton, Dept. of Biochemistry, University of St. Andrews, Irvine
Building, North Street, St Andrews, KY16 9AL; J. C. Neil and A. Terry, Molecular Oncology Laboratory, University of Glasgow, Dept. of Veterinary Pathology, Bearsden, Glasgow Scotland G61 1QH; J. K. Ball, Dept. of Microbiology, University Hospital Queens Medical Centre, Nottingham, NG7 2UH; R. Banerjee, M. Igo, R. Izumi, U. Datta and A. Dasgupta, Dept. of Microbiology and Immunology, UCLA School of Medicine, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA; J. Barr. Institute of Virology, University of Glasgow, Church Street, Glasgow, Scotland, G11 5JR; J. W. McCauley, Compton Laboratory, Institute of Animal Health, Compton, Newbury, Berkshire RG20 7NN; A. Bridgen and R.M. Elliott, Division of Virology, Institute of Biological and Life Sciences, University of Glasgow, Church Street,
Glasgow, Scotland, G11 5JR; B.A. Usmani, A. Fassati and G. Dickson, School of Biological Sciences, Division of Biochemistry, Royal Holloway College, University of London, Egham, Surrey TW20 OEX
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Investigation of RNA Virus Genome Structure
Mutagenesis of RNA Virus Genomes
Analysis of Transcriptional Control in RNA Virus Infections
Analysis of RNA Virus-encoded Proteinases
Detection and Analysis of Host Gene Targets for Oncogenic Retroviruses
Analysis of RNA Virus Quasispecies
In Vitro Replication of RNA Viruses
Packaging of Segmented and non-segmented RNA Virus Genomes
RNA Virus Reverse Genetics
Development of RNA Virus Vectors for Gene Delivery
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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