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Molecular and Cellular Glycobiology
Second Edition
Edited by Minoru Fukuda and Ole Hindsgaul
312 pages
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1 colour plate, 2 halftones, numerous line drawings
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246x189mm
978-0-19-963806-2
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Paperback
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07 September 2000
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This item is printed to order and supplied on a firm sale basis. Items which are printed to order are normally despatched and charged within 5-10 days.
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- Covers the structure, biosynthesis and function of carbohydrates including carbohydrate-deficient diseases and carbohydrates in development and disease.
- Includes development in therapeutic drugs based on carbohydrates.
- Well illustrated.
Molecular and Cellular Glycobiology covers the recent progress in understanding the biological roles of carbohydrates and includes basic knowledge of carbohydrates in mammals. Emphasis is on structure, biosynthesis and function of carbohydrates in development and disease. In particular, biological significance in immune cells, neural cells and cytoplasmic and nuclear proteins are thoroughly described. In addition, Molecular and Cellular Glycobiology updates the knowledge of diseases caused by anomalies of carbohydrate biosynthesis and the animal models used to investigate the physiological roles of carbohydrates including carbohydrates attached to lipids. Various attempts to develop therapeutic
agents based on carbohydrates are also described. Molecular and Cellular Glycobiology covers recent developments in a comprehensive yet focused manner and will be of interest to anyone with a basic knowledge of carbohydrates.Readership: Graduate students, postdoctoral researchers, and lecturers with a basic knowledge of carbohydrates. It will also be of interest to advanced undergraduates studying glycobiology.
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Edited by Minoru Fukuda, The Burnham Institute, University of California, San Diego, and Ole Hindsgaul, Department of Chemistry, University of Alberta, Canada Contributors:
Minoru Fukuda, The Burnham Institute, U California San Diego, USA; Harry Schachter, Department of Biochemistry, Hospital for Sick Children, CANADA; Gerald Hart, Department of Biology and Chemistry, John Hopkins University Med School, USA; Yoshio Hirabayashi, Group Leader Laboratory for Cellular Glycobiology, Institute of Physical and Chemical, JAPAN; Pamela Stanley, Department of Cell Biology, Albert Einstein College of Medicine, USA; Ole Hindsgaul,
Department of Chemistry, University of Alberta, Canada; Urs S. Rutishauser, Memorial Sloan-Kettering Cancer Centre, New York, USA; John Lowe, Howard Hughes Medical Institute, University of Michigan Medical School, USA; Michiko Fukuda, The Burnham Institute, U California San Diego, USA
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Cell surface carbohydrates: cell-type specific expression
Carbohydrate recognition in leukocyte-endothelial cells
Polysialic acid in neural cell development: roles, regulation, and mechanism
Carbohydrate-deficient glycoprotein syndromes and congenital dyserythropoietic anaemia type II (HEMPAS)
Functions of Carbohydrates Revealed by transgenic technology
Function and significance of O-GlcNAc glycoproteins in the nucleus and cytoplasm
Roles of sphingolipids and glycosphingolipids in biological membranes
Carbohydrates in medicine
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