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Human Cytogenetics: Constitutional Analysis
A Practical Approach
Third Edition
Edited by Denise Rooney
304 pages
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8 8 colour plates and numerous tables and figures
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246x189mm
978-0-19-963839-0
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Paperback
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05 April 2001
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This item is printed to order and supplied on a firm sale basis. Items which are printed to order are normally despatched and charged within 5-10 days.
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- New design.
- Over 90 figures some in colour. Combines classical and molecular technologies.
Human Cytogenetics: Constitutional Analysis covers all basic aspects of human cytogenetic study other than malignancies and abnormalities. They are covered in a separate volume. Since the publication of the 2nd edition in 1992, there have been major advances in technology and the emphasis of this new edition is on the spectrum of technologies available to conventional and molecular cytogenetics. Perhaps the largest new development has been the transition of fluorescence in situ hybridization to an essential tool for all cytogenetecists and consequently its use in chromosome analysis is covered in detail. Another important new technology
to be described in detail is computerised image analysis. The conventional techniques have not been forgotten, with chapters on chromosome staining and banding techniques and meiotic studies. New authors have been brought in to take a fresh look at lymphocyte culture and prenatal diagnosis. As before, there is an introduction to human chromosomes, their analyses, and the application of cytogenetic investigations to clinical practice. There is also an appendix on health and safety concerns in the cytogenetics laboratory. This book will be invaluable to any scientists using basic cytogenetics and along with its sister volume Human Cytogenetics: Malignancy and Acquired Abnormalities will be an essential purchase for any cytogenetics laboratory. The volumes are available individually or as a
set.Readership: Scientists doing basic chromosome research and clinical genetic diagnostics.
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Edited by Denise Rooney, NE London Regional Cytogenetics Laboratory Contributors:
I. E.Cross, Cytogenetics Laboratory, Northern Genetics Service, Newcastle upon Tyne, U.K.; J. Wolstenholme, Cytogenetics Laboratory, Northern Genetics Service, Newcastle upon Tyne, U.K.; H. J. Clouston, Cytogenetics Laboratory, Northern Genetics Service, Newcastle upon Tyne, U.K.; T. Boyle, Wessex Regional Genetics Laboratory, Salisbury Health Care NHS Trust, U.K.; D. Griffin, Department of Biology and Biochemistry, Brunel University, U.K.; P.A. Benn, Human Genetics Laboratories, University of Connecticut Health Centre School of Medicine, U.S.A.; U. Tantravahi,
Cytogenetics and Molecular Genetics Laboratory, U.S.A.; J. Wolstenholme, Cytogenetics Laboratory, Northern Genetics Service, Newcastle upon Tyne, U.K.; J. Burn, Human Genetics Unit, School of Biochemistry and Genetics, University of Newcastle upon Tyne, U.K.; L.U. Kearney, MRC Molecular Haematology Unit, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford; V.J. Buckle, MRC Molecular Haematology Unit, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford; M. A. Hulten, Medical Research Institute, Department of Biological Sciences, University of Warwick. U.K.
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""This is the much needed and awaited update of a cytogenetics reference last published in 1992 ... Both volumes of this 3rd rdition are outstanding contributions to the practice of clinical cytogenetics and should be fixtures in every cytogentics laboratory. The editor will be pleased to note (as she mentioned in her preface) that my copies sit prominently on my desk and are severely "dog-eared""" - Kent E Opheim, PhD, Children's Hospital and Regional Medical Center
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An introduction to human chromosomes and their analyses
Lymphocyte culture
The cytogenetics of pregnancy
Chromosome staining and banding techniques
The application of cytogenetic investigations to clinical practice
The application of flurorescence in situ hybridisation to chromosome analysis
Meiotic studies in man
Microscopy, photography and computerised image analysis systems
Safety Appendix
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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