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Antimicrobial Chemotherapy
Fifth Edition
David Greenwood, Roger Finch, Peter Davey, and Mark Wilcox
504 pages
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numerous line drawings and tables, 1 map, 3 black and white illustrations. 4 halftones
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234x156mm
978-0-19-857016-5
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Paperback
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11 January 2007
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- An essential guide to the principles of antimicrobial chemotherapy, providing an aid to informed, rational prescribing
- Covers the basic properties of antibacterial, antifungal, antiparasitic and antiviral (including antiretroviral) drugs
- Provides an historical introduction, to place the subject in context
- Therapeutic use is covered, both the general principles and site-specific, practical advice
- Includes commentary on the way drugs are developed and marketed
- Covers issues specific to both the developed and developing world
New to this edition - Includes new agents and therapeutic insights
- New chapter on guidelines, formularies and antimicrobial drug policies
- New two-colour text design aids navigation
Instilling good prescribing habits in young doctors is essential for the benefit of patients and to preserve the value of the antibiotic revolution that altered medical practice in the second half of the twentieth century. These concerns underlie the approach taken in the new edition of this successful book.
The text provides a comprehensive and up-to-date account of the principles of antimicrobial chemotherapy as an aid to informed, rational prescribing. Care is taken to address all aspects of antimicrobial drug use, including those specific to developed and developing countries of the world. The authors are international experts with a long
standing interest in the role of education as a means of promoting an understanding of the benefits and limitations of antimicrobial chemotherapy in physicians, surgeons and other health care workers. The book offers a structured approach to the subject in four themed sections, each of several chapters. A historical introduction is followed by a section outlining the basic properties of antibacterial, antifungal, antiparasitic and antiviral (including antiretroviral) drugs. The next section explains the various facets of antimicrobial drug resistance - which threatens to undermine the continued efficacy of antimicrobial agents - and effective ways of countering the threat. Therapeutic use is covered in two sections: one introduces readers to the general principles that inform the rational
prescribing of antimicrobial drugs; the second deals with practicalities of the use of antimicrobial agents in specific clinical conditions. The book ends with a description of the ways in which drugs are developed and marketed. There are extensive recommendations for further reading.Readership: Medical students, junior doctors preparing for their membership exams, nurses, pharmacists, medical microbiologists, those in the pharmaceutical industry responsible for research, development and sales, and students of health care sciences all need to know about antimicrobial agents, prescribing habits, and therapeutic drugs.
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David Greenwood, Emeritus Professor of Antimicrobial Science, University of Nottingham Medical School, UK, Roger Finch, Professor of Infectious Diseases, University of Nottingham Medical School, UK, Peter Davey, Professor of Pharmacoeconomics, University of Dundee; Honorary Consultant in Infectious Diseases, NHS Tayside, Dundee, UK, and Mark Wilcox, Professor of Medical Microbiology, University of Leeds; Consultant and Director of Infection Prevention & Control, Leeds Teaching Hospitals NHS Trust, UK
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"...a well-written, common-sensical guide to antimicrobials...strongly recommended to medical student as an excellent place to begin learning about the way that antimicrobials work and the treatment of infection." - Journal of Infection "Its undoubted strength is the clinical context within which the information is portrayed and the sections on antimicrobial resistance and principles of antimicrobial usage are worth the price of the book alone." - British Journal of Hospital Medicine "...an excellent blend of basic science and clinical application...whilst providing an everyday guide to the management of infection for the junior prescriber, it should also inform the more experienced clinician seeking a
broader and deeper understanding of antimicrobial chemotherapy. The facts are clearly presented using a captivating approach, and the authors have succeeded in imparting a large volume of information in a compact and unintimidating manner...a text that prescribers of antimicrobial chemotherapy should find invaluable when confronting the challenging issues posed by infections in the current era." - Journal of Antimicrobial Chemotherapy "...the information that is portrayed and the sections on antimicrobial resistance and principles of antimicrobial usgae are worth the price of the book alone. ...This is therefore a book that I can easily recommend, and one that I wish I had been introduced to sooner. s" "This is a useful overview of antimicrobial therapy.
The authors provide essential information to answer several basic questions each prescriber should ask when writing antimicrobial prescriptions: what agent am I choosing, why am I choosing it, and how can I make a better choice? The information is updated in the hopes of giving healthcare providers a sound knowledge base to continue good prescribing practices." - Doody's Notes "this book is great value for money and one that its owner will revisit again and again." - Pharmaceutical Journal
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Historical Introduction
Part I: General properties of antimicrobial agents
1: Inhibitors of bacterial cell wall synthesis
2: Inhibitors of bacterial protein synthesis
3: Synthetic antibacterial agents and miscellaneous antibiotics
4: Antifungal agents
5: Antiprotozoal and anthelminthic agents
6: Antiviral agents
7: Antiretroviral agents
Part 2: Resistance to antimicrobial agents
8: The problem of resistance
9: Mechanisms of acquired resistance
10: Genetics of resistance
11: Control of the spread of resistance
Part 3: General principles of usage of antimicrobial agents
12: Use of the laboratory
13: General principles of the treatment of infection
14: Pharmacokinetics
15: Prescribing for children and the elderly
16: Adverse reactions
17: Chemoprophylaxis
18: Guidelines, formularies and antimicrobial policies
Part 4: Therapeutic use of antimicrobial agents
19: Respiratory tract infections
20: Urinary infections
21: Gastrointestinal infections
22: Bacteraemia and endocarditis
23: Skin and soft tissue infections
24: Bone and joint infections
25: Mycobacterial disease
26: Infections of the central nervous system
27: Viral infections
28: Infection in immunocompromised patients including HIV/AIDS
29: Sexually transmitted infections
30: Parasitic diseases
31: Topical use of antimicrobial agents
32: Postscript: The development and marketing of antimicrobial drugs
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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