Readership: An advanced textbook suitable for graduate level students as well as professional researchers in the fields of gerontology, pathology, functional genomics, biochemistry and evolutionary biology.
Jan Vijg, Buck Institute for Age Research, Novato, California, USA
"'This is a work of real scholarship, a critical account of a huge swathe of work The sharp focus on one type of damage, the excellent writing style and the well argued, personal perspective of the author contrive to keep the reader going.' - Nature"
"'The book represents a substantial effort and documents the broad and deep insight that Vijg has into the field of aging. It should greatly stimulate interest and the entry of promising new scientists into the field and will help heighten the profile and importance of aging research in general.' - Nature Genetics"
Preface 1: Introduction 2: The Logic of Aging 3: Genome Structure and Function 4: Genome Maintenance 5: Genome Instability and Accelerated Aging 6: The Aging Genome 7: From Genome to Phenome 8: A Genomic Limit to Life? References and Glossary Literature References