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Neuropathic Pain
Mechanisms, Diagnosis and Treatment
Edited by David M. Simpson, Edited by Justin C. McArthur, and Robert H. Dworkin
529 pages
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67
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178x254mm
978-0-19-539470-2
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Hardback
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21 June 2012
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- Unique chapters covering clinical trial design and ethical, legal, and social issues that directly address current challenges in pain treatment and research.
- Offers plentiful figures and tables.
The incidence of neuropathic pain continues to rise, yet it is an affliction often misdiagnosed or inadequately treated. Although in recent years considerable research has been dedicated to understanding its mechanisms, there have been few advances in treatment. The contributors to this book are internationally renowned leaders in the fields of peripheral neuropathy and neuropathic pain. They discuss clinical approaches to diagnosis and treatment of neuropathic pain, its underlying mechanisms, and strategies for prevention. In addition, chapters cover timely issues, including legal and ethical concerns surrounding pain treatment, the status of clinical trial methods, and
educational efforts. Comprehensive yet concise, this book serves as a guide for diagnostic approaches and treatment of neuropathic pain for the student, resident, practicing physician, researcher, and specialist.Readership: Residents and fellows (internal medicine, neurology, anesthesiology), primary care clinicians, neurologists, anesthesiologists, and other pain specialists.
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Edited by David M. Simpson, Professor of Neurology, Mount Sinai Medical Center, Edited by Justin C. McArthur, Professor of Neurology, Pathology, Medicine, and Epidemiology, Johns Hopkins University School of Medicine, and Robert H. Dworkin, Professor of Anesthesiology, Neurology, Oncology, and Psychiatry, University of Rochester School of Medicine and Dentistry David M. Simpson, MD is Professor of Neurology and Director of Neuromuscular Division, Director of Clinical Neurophysiology Laboratories, and Director of Neuro-AIDS Program at Mount Sinai Medical Center in New York.
Justin C. McArthur, MBBS, MPH is Professor of Neurology, Pathology and Epidemiology and Director of Department of Neurology at Johns Hopkins University School of Medicine in Baltiomore, Maryland.
Robert H. Dworkin, PhD, is Professor of Anesthesiology, Neurology, Oncology, and Psychiatry, and Professor at the Center for Human Experimental Therapeutics at the University of Rochester School of Medicine and Dentistry in Rochester, New York. Contributors: W. David Arnold, MD, Assistant Professor of Neurology, Ohio State University, Columbus, OH; Aditya Bardia, MD, MPH, Johns Hopkins Kimmel Comprehensive Cancer Center, Baltimore, MD; Ralf Baron, Prof. Dr. med., Head, Division of Neurological Pain Research and Therapy, Vice Chair, Department of Neurology, Universitätsklinikum Schleswig-Holstein, Kiel, Germany; Tamara B. Bockow, University of Pennsylvania School of Medicine,
Philadelphia, PA; Jörgen Boivie, MD, PhD, Department of Neurology, University Hospital, Uppsala, Sweden; Brian Callaghan, MD, Associate Director, Amyotrophic Lateral Sclerosis (ALS) Clinic, University of Michigan, Ann Arbor, MI; William W. Campbell, MD, MSHA, Department of Neurology, Uniformed Services University of Health Sciences, Bethesda, MD; Craig G. Carroll, DO, Department of Neurology, Naval Medical Center, Portsmouth, VA; Vinay Chaudhry, MD, Professor, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD; Hsinlin Thomas Cheng, MD, PhD, Assistant Professor, Department of Neurology, University of Michigan, Ann Arbor, MI; Paul J. Christo, MD, MBA, Pain Management Specialist, Johns Hopkins Hospital, Baltimore, MD; Steven P. Cohen, MD, Associate
Professor,Department of Anesthesiology/Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; Ross C. Donehower, MD, Professor of Oncology and Medicine, Johns Hopkins University School of Medicine, Director, Division of Medical Oncology, Johns Hopkins Oncology Center, Baltimore, MD; Kathryn J. Elliott, MD, JD, MSc, Assistant Professor of Neurology, Mount Sinai School of Medicine, New York, NY; Eva L. Feldman, MD, PhD, Russell N. DeJong Professor of Neurology, University of Michigan, Ann Arbor, MI; Howard L. Fields, MD, PhD, Director of Human Clinical Research, Gallo Center, Professor of Neurology and Physiology, University of California, San Francisco, San Francisco, CA; Roy Freeman, MD, Professor of Neurology, Harvard Medical School, and Center for Autonomic
and Peripheral Nerve Disorders, Beth Israel Deaconess Medical Center, Boston, MA; Christopher H. Gibbons MD, MMSc., Assistant Professor of Neurology, Beth Israel Deaconess Medical Center, Boston, MA; Ian Gilron, MD, MSc, FRCPC, Director of Clinical Pain Research, Professor of Anesthesiology and Pharmacology & Toxicology, Queen's University, Kingston, Ontario, Canada; John W. Griffin, MD, Professor of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD; Scott Haldeman, DC, MD, PhD, Clinical Professor, Department of Neurology, University of California, Irvine, and Adjunct Professor, Department of Epidemiology, University of California, Los Angeles, and Research Division, Southern California University of Health Sciences, Whittier, CA; Per Hansson, MD, DMSci, DDS, Specialist
in Neurology and Pain Medicine, Karolinska University Hospital, and Professor of Clinical Pain Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; R. Norman Harden, MD, Medical Director, Center for Pain Studies, Center for Pain Management, Rehabilitation Institute of Chicago, and Associate Professor, Physical Medicine & Rehabilitation, Northwestern University, Chicago, IL; Spencer Heaton, MD, Staff Physician, International Pain Medicine, Desert Pain Institute, Mesa, AZ; Ahmet Höke, MD, PhD, Professor of Neurology and Neuroscience, Director, Neuromuscular Division, Johns Hopkins School of Medicine, Baltimore, MD; Steven H. Horowitz, MD, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Mark P. Jensen,
PhD, Professor and Vice Chair for Research, Department of Rehabilitation Medicine, University of Washington, Seattle, WA; Christina Jensen-Dahm, Department of Neurology, University of Copenhagen, Rigshospitalet, Denmark; John T. Kissel, MD, Director, Division of Neuromuscular Medicine, Professor of Neurology, Associate Professor of Pediatrics, Ohio State University, Columbus, OH; Michael Lim, MD, Assistant Professor of Neurosurgery and Oncology, Director of the Metastatic Brain Tumor Center, Director of Brain Tumor Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD; John D. Markman, MD, Associate Professor, Department of Neurosurgery, University of Rochester School of Medicine and Dentistry, Rochester, NY; John M. Mayer, DC, PhD, College of Medicine and School of
Physical Therapy & Rehabilitation Sciences, University of South Florida, Tampa, FL; Michael R. Moore, Department of Psychology, Willamette University, Salem, OR; Beth B. Murinson, MS, MD, PhD, Assistant Professor, Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD; Trang Nguyen, Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD; Anne Louise Oaklander, MD, PhD, Associate Professor of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Alec B. O'Connor, MD, MPH, Associate Professor of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY; Amanda Peltier, MD, MS, Assistant Professor, Neurology, Vanderbilt Medical Center, Nashville, TN; Karin L. Petersen, MD, Associate Adjunct Professor of
Neurology, University of California, San Francisco, San Francisco, CA; Srinivasa N. Raja, MD, Professor, Department of Anesthesiology/Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; Pablo Recinos, MD, Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD; Gadi Revivo, DO, Center for Pain Management, Rehabilitation Institute of Chicago, Northwestern University, Chicago, IL; Kathryn Richardson, MOTR/L, Center for Pain Management, Rehabilitation Institute of Chicago, Chicago, IL; Tamara S. Ritsema, MP, MMSc, PA-C, Assistant Professor of Health Care Sciences, George Washington University, Washington, DC; Jessica Robinson-Papp, MD, Assistant Professor of Neurology, Mount Sinai Medical Center, New York, NY; Ricardo Roda, MD, PhD, Clinical Fellow,
Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD; Michael C. Rowbotham, MD, Professor of Clinical Neurology and Anesthesia, University of California, San Francisco, San Francisco, CA; Michelle Shufelt, DPT, Center for Pain Management, Rehabilitation Institute of Chicago, Chicago, IL; J. Robinson Singleton, MD, Associate Professor, Neurology, University of Utah, Salt Lake City, UT; A. Gordon Smith, MD, Associate Professor, Neurology, Pathology, University of Utah, Salt Lake City, UT; Rolf-Detlef Treede, MD, Professor of Neurophysiology, Center for Biomedicine and Medical Technology Mannheim (CBTM), Ruprecht-Karls-University of Heidelberg, Mannheim, Germany; Andrew W. Varga, MD, PhD, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA; Gunnar
Wasner, MD, Consultant Neurologist, Division of Neurological Pain Research and Therapy, Department of Neurology, Christian-Albrechts-Universität, Kiel, Germany; Kayode A. Williams, MD, MBA, FFARCSI, Assistant Professor of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
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Foreword
Preface
Contributors
1. Neuropathic Pain: A Brief Conceptual History
2. Peripheral and Central Mechanisms of Neuropathic Pain
3. Experimental Approaches to Neuropathic Pain
4. Drug Discovery for Neuropathic Pain
5. Definitions, Anatomical Localization, Signs and Symptoms of Neuropathic Pain
6. Diagnostic Testing: NCS, QST, Autonomic Testing, Skin/Nerve BX, Pain Scales
7. Psychosocial Aspects of Neuropathic Pain
8. Pharmacology of Neuropathic Pain
9. Understanding and Interpreting Neuropathic Pain Clinical Trials
10. Ethical, Legal and Social Issues in the Management of Neuropathic Pain
11. Painful Diabetic Neuropathy
12. HIV-Associated Distal Symmetric Polyneuropathy
13. Heritable Neuropathies
14. Cancer Associated Neuropathic Pain and Paraneoplastic Syndromes
15. Herpes Zoster and Postherepetic Neuralgia
16. Immune Mediated Neuropathies
17. Entrapment Syndromes
18. Traumatic Peripheral Nerve Injuries
19. Chronic Postsurgical Pain
20. Central Neuropathic Pain
21. Spinal Root Disease: Radiculopathy and Arachnoiditis
22. The Complex Regional Pain Syndrome
23. Trigeminal Neuralgia and Atypical Facial Pain
24. Metabolic, Endocrine, and Other Toxic Neuropathies
25. Complementary and Alternative Medicine for Neuropathic Pain
26. Neuropathic Pain: An Interdisciplinary Rehabilitation Approach
27. Preventing Neuropathic Pain in Experimental Models and Predictable Clinical Settings
28. Peripheral Neuropathy: Educating Patients and Providers
Index
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The specification in this catalogue, including without limitation price, format, extent, number of illustrations, and month of publication, was as accurate as possible at the time the catalogue was compiled. Occasionally, due to the nature of some contractual restrictions, we are unable to ship a specific product to a particular territory. Jacket images are provisional and liable to change before publication.
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