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Readership: Human genetic variation has implications across a broad range of disciplines and this text neatly consolidates work in diverse fields to highlight common themes and principles. An accessible style and the extensive use of illustrations promote its relevance to a broad audience ranging from those interested in human and population genetics to molecular biologists, evolutionary biologists, biological anthropologists and individuals working in the health sciences and clinical medicine.
Julian C. Knight, Wellcome Trust Centre for Human Genetics, University of Oxford, UK
1: Lessons From Haemoglobin 2: Finding Genes and Specific Genetic Variants Responsible for Disease 3: Cytogenetics and Large Scale Structural Genomic Variation 4: Submicroscopic Structural Variation in Health and Susceptibility to Disease 5: Submicroscopic Structural Variation and Genomic Disorders 6: Segmental Duplications and Indel Polymorphisms 7: Tandem Repeats 8: Mobile DNA Elements 9: SNPs, HapMap and Common Disease 10: Fine Scale Sequence Diversity and Signatures of Selection 11: Genetics of Gene Expression 12: Extreme Diversity in the Major Histocompatibility Complex 13: Parasite Wars 14: Human Genetic Diversity and HIV: Lessons From a War Fought on Many Fronts 15: Concluding Remarks and Future Directions Glossary References Index
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