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Chromatin Structure and Gene Expression
Second Edition
Edited by Sarah Elgin and Jerry Workman
360 pages
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6 plates, 4 halftones, numerous line illustrations
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246x189mm
978-0-19-963890-1
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Paperback
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23 November 2000
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This item is printed to order and supplied on a firm sale basis. Items which are printed to order are normally despatched and charged within 5-10 days.
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- Provides the ideas, overview and results by leading scientists of the most exciting work in this field.
- Topic is central to the interests of many biologists.
Since publication of the first edition in 1995, there have been significant advances and understanding of chromatin structure and its relation to gene expression. These include a high-resolution structure of the nucleosome core, discovery of the enzymes and complexes that mediate histone acetylation and deacetylation, discovery of novel ATP-dependent chromatin remodeling complexes, new insights into nuclear organization and epigenetic silencing mechanisms. In light of these advances, Chromatin Structure and Gene Expression (2ed.) includes updated chapters and additional material that introduce new concepts in the process of gene regulation in
chromatin.Readership: Researchers and advanced students interested in the effect of chromatin structure on gene expression.
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Edited by Sarah Elgin, Department of Biology, Washington University, St Louis, and Jerry Workman, Department of Biochemistry and Molecular Biology, Howard Hughes Medical Institute, Pennsylvania State University Contributors:
C. David Allis, Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine; Genevieve Almouzni, Nuclear Dynamics and Genome Plasticity, Institu Curie-Section Recherche, France; Michelle Barton, Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati; Peter B. Becker, Adolf-Butenandt-Institut, Molekularbiologie, Germany; Andrew S. Belmont,
Cell and Structural Biology, University of Illinois; Shelley L. Berger, The Wistar Institute, Philadelphia; Wendy A. Bickmore, Cell Genetics Section, MRC Human Genetics Unit, Edinburgh; Adrian Bird, Institute of Cellular and Molecular Biology, University of Edinburgh; Bradley R. Cairns, Department of Oncological Sciences, Huntsman Cancer Institute, USA; Victor G. Corces, John Hopkins University, Department of Biology, USA; Joel C. Eissenberg, Department of Biochemistry, St Louis University, School of Medicine; Sarah C. R. Elgin, Department of Biology, Washington University; Gary Felsenfeld, Molecular Biology NIDDKD, USA; Andrew Free, Institute of Cell and Molecular Biology, University of Edinburgh; Lisa Freeman-Cook, University of California, Department of Biology; Patrick A. Grant,
Department of Biochemistry and Molecular Genetics, University of Virginia Health Sciences; Michael Grunstein, University of California, Molecular Biology Institute; Wolfram Hoerz, Adolf-Butenandt-Institut, Molekularbiologie, Universitataet Muenchen, Germany; Rohinton Kamakaka, National Institutes of Child Health and Development, National Institutes of Health, USA; Paul D. Kaufman, Lawrence Berkeley National Laboratory and Department of Molecular and Cell Biology, University of California; Robert E. Kingston, Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School; Nicola L. Mahy, Cell Genetics Section, MRC Human Genetics Unit, UK; Renato Paro, Zentrum fur Molekulare Biologie, Universitat Heidelberg, Germany; Lorraine Pillus, University of California,
Department of Biology; Timothy J. Richmond, Eth-Hoenggerberg, Institute fur Molekularbiologie un Biophys, Zurich; Sharon Roth, Department of Biochemistry and Molecular Biology, Program in Genes and Development, U.T.M.D. Anderson Cancer Centre; Christopher J. Schoenherr, Princeton University, 128 Lew Thomas Lab, USA; M. Mitchell Smith, University of Virginia, Microbiology, USA; Shirley M. Tilghman, Princeton University, Lewis Thomas Lab, USA; Toshi Tsukiyama, Fred Hutchinson Cancer Research Centre, Basic Sciences Division, USA; Tudorita Tumbar, Cell and Structural Biology, University of Illinois, USA; Maria Vogelauer, University of Carlifornia, 340 Molecular Biology Institute; Jonathan Widom, Northwestern University, Department of Chemistry, USA; Fred Winston, Harvard University USA; Alan
P. Wolffe, Sangamo Biosciences Inc., USA; Jerry L. Workman, Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biology, The Pennsylvania State University; Carl Wu, Laboratory of Molecular Cell Biology, National Cancer Institute, Bethesda, USA
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Nucleosome and Chromatin Structure
DNA Replication, Nucleotide Excision Repair and Nucleosome Assembly
Chromatin Structure and Control of Transcription in Vivo
The Genetics of Chromatin Function
The SWI/SNF family of remodeling complexes
ATP-Dependent Chromatin Remodeling and Assembly by the ISWI Complexes
Histone Acetyltransferase/Transcription Coactivator Complexes
Histone Deacetylation: mechanisms of repression
Developmental Regulation of Chromatin Function and Gene Expression
Chromatin Contributions to Epigenetic Transcriptional States in Yeast
Epigenetic Regulation in Drosophila: unraveling the conspiracy of silence
Epigenetics in Mammals
Chromatin Boundaries
Linking Large-Scale Chromatin Structure with Nuclear Function
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