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Cell Adhesion
Edited by Mary C Beckerle
426 pages
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numerous figures and halftones
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246x189mm
978-0-19-963872-7
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Hardback
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21 February 2002
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This item is printed to order and supplied on a firm sale basis. Items which are printed to order are normally despatched and charged within 5-10 days.
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- Comprehensive review of the cell adhesion field - including structure and function of cell adhesion molecules as well as a review of their roles in development and disease
- Coverage of many cell adhesion molecules in a single volume
- Great resource for students, teachers and researchers
Cell adhesion plays a central role in development and disease. Cell adhesion to particular ligands can affect cytoskeletal organization and cell polarity, cell proliferation, and gene expression. This book is divided into two parts. The first section provides a discussion of the structure and function of the seven major classes of cell adhesion molecules: integrins, cadherins, selectins, heparan sulfate proteoglycans, the immunoglobulin superfamily, the ADAMs proteins, and transmembrane protein tyrosine phosphatases. The roles of these cell adhesion proteins in important processes such as cell mediated immunity, development and disease are discussed. In the second
section, the molecular organization and function of junctional complexes, regions of the cell surface that are highly specialized for cell adhesion, are examined. Junctional complexes are now known to mediate adhesive interactions and contribute to transmembrane signaling events that dramatically influence cell behaviour. The biochemical organization of the adhesive membranes and the molecular mechanisms by which they transmit information to the cell are addressed.
Written by contributors among the most prominent in the field, Cell Adhesion covers a wide range of topics in a single volume. It will be a great resource for students, teachers and researchers.Readership: Graduate students and
advanced undergraduates in cell and developmental biology; cell biology researchers; developmental biology researchers; university lecturers teaching cell and developmental biology; cancer researchers.
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Edited by Mary C Beckerle, Huntsman Cancer Institute and Department of Biology, University of Utah, USA Contributors:
Leslie J. Bannon, Mary C. Beckerle, Merton Bernfield, Dora Bigler, Margaret A. Bolton, Susann M. Brady-Kalnay, Keith Burridge, Michellee Chen, Douglas W. Desimone, Bette J. Dzamba, Mikio Furuse, Lawrence E. Goldfinger, Cara J. Gottardi, Kathleen J. Green, Barry M. Gumbiner, Masahiko Itoh, Jonathan C.R. Jones, Rodger P. McEver, Carien M. Niessen, Pyong Woo Park, Lynda Peterson, Glenn L. Radice, Ofer Reizes, Yuji Takahashi, Masatoshi Takeichi, Shoichiro Tsukita, Hansjurgen Volkmer, Judith M. White,
Tyra G.
Wolfsberg
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1: Hansjurgen Volkmer: The immunoglobulin superfamily of cell adhesion molecules
2: Rodger P McEver: Selectins
3: Glenn L Radice and Masatoshi Takeichi: Cadherins
4: Bette Dzamba, Margaret Bolton and Douglas Desimone: The integrin family of cell adhesion molecules
5: Ofer Reizes, Pyong Woo Park, and Merton Bernfield: Cell surface heparan sulfate proteoglycans
6: Judith White, Dora Bigler, Michellee Chen, Yuji Takahashi, and Tyra Wofsberg: ADAMs
7: Susann Brady-Kalnay: Protein tyrosine phosphatases
8: Cara Gottardi, Carien Niessen, Barry Gumbiner: The adherens junction
9: Lynda Peterson and Keith Burridge: Focal adhesions and focal complexes
10: Leslie Bannon, Lawrence Goldfinger, Jonathan Jones, Kathleen Green: Desmosomes and hemidesmosomes
11: Shoichiro Tsukita, Mikio Furuse, Masahiko Itoh: The tight junction
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