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Medicinal Inorganic Chemistry
Edited by Jonathan L. Sessler, Susan R. Doctrow, Thomas J. McMurry, and Stephen J. Lippard
464 pages
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24 halftones, 143 line illus.
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228x152mm
978-0-8412-3899-2
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Hardback
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14 July 2005
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This item is printed to order and supplied on a firm sale basis. Items which are printed to order are normally despatched and charged within 5-10 days.
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- Selling point: This book is a compilation of current topics written by experts in the field of medicinal inorganic chemistry. While pharmaceutical chemists are familiar with traditional medicinal chemistry of organic molecules, the potential of metal complexes as pharmaceutical agents and the role of metals in disease has been traditionally underappreciated. This work will be an important resource for those working in the field of drug discovery and for those interested in understanding metal-based physiology.
This book, a compilation by experts in the field, is designed to provide an introduction to the area of medicinal inorganic chemistry and
to summarize current, state-of-the-art developments in the field. Medicinal inorganic chemistry represents a key thrust area in medicine and biological inorganic chemistry. It is one of great current excitement and achievement. The field of metals in medicine represents an approximate $3 billion dollar a year industry, with successes in the area of Tc- and Gd-based imaging agents and Pt-based cancer therapeutics being major contributors to this bottom line. It has become increasingly apparent, however, that metal-based pharmaceuticals can play a prominent role in areas outside of imaging and oncology, including in those associated with the diagnosis and treatment of metabolism- and genetic disorders, cardiovascular disease, gene therapy, inflammation, reperfusion injury, stroke,
diabetes, ALS, malaria, and neurological disease to name but a few. A objective of this book, therefore, is to highlight these opportunities for future advances and to foster further interactions between those working in the metal-based drug development, including imaging agents, and those engaged in the more classic pharmaceutical industries.
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Edited by Jonathan L. Sessler, Roland K. Pettit Centennial Professor, University of Texas at Austin, Susan R. Doctrow, Eukarion, Inc., Thomas J. McMurry, Vice President, Research, EPIX Pharmaceuticals, Inc., and Stephen J. Lippard, Noyes Professor, Massachusetts Institute of Technology
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"A worthwhile addition to your library, both personal and institutional, if this is your particular field of interest." - Steve Mitchell, Medicinal Inorganic Chemistry
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